Topics: More and more information on the release, exposure and possible toxicological effects of nano-objects is being produced. The understanding of fundamental and general aspects in these different research fields is steadily increasing. The main aim of this workshop is to bring together experts in these different research fields to build a bridge from exposure to health effects for manufactured nanomaterials. The discussions will start with a presentation of the state of the art and of our future needs and will move onto cover all the relevant aspects bridging the fields of release and exposure with toxicological studies.